(4 replies) Dosage of Strontium. (Moise H, Adachi JD, Chettle DR, et al. Hope this helps, Lara. I am not a physician. If you would like to read up about hormone testing and the 24 Hour Urine, I wrote an article for physicians about all this that is available at Longevity Medicine Review heres a link: None of the articles however, showed 170 mg to be more effective than 680 mg. I hope this answers your question and inspires you to try AlgaeCal, which significantly improved my bone density in only 10 months, so I can vouch for it personally, and this is why I am doing what I can to help get the word out about AlgaeCal. You want to be sure what you are getting is not adulterated or contaminated. I looked but could find no other study that has replicated these findings or reported similar findings since. Stable strontium itself has never been found to cause any harmful effects with one caveat: to maintain proper balance between calcium and strontium, more calcium than strontium must be consumed. Moreover, too much fiber and fructose in fruits can also make slow down your digestive system if eaten on an empty stomach. There's a lot of misinformation in the posts above. The key point here is that when Strontium Boost is used and the possibility of overestimation is factored in the result is still an increase in BMD averaging 0.91 to 0.95% annually. In addition to its antiresorptive activity, strontium was found to have anabolic activity in bone and thus may have significant beneficial effects on bone balance in normal and osteopenic animals. My question has to do with breast cancer. It must have been something else that upset my stomach and I am now taking all the pills with no side effects. Sr21 is taken up into bone by two different mechanisms: (1) an initial rapid mode, depending on osteoblastic activity, which is eventually saturated, and whereby Sr21 is taken up by ionic exchange with bone Ca21, binding of Sr21 to preosteoid proteins, or combinations of these; and (2) a second slower mechanism involving the incorporation of Sr21 into the crystal lattice of the bone mineral. I have tried taking it different times of day and I have tried taking only one capsule, either way I have a headache. The study found that the amount of bone loss directly correlated to the bacterial load found in the bones. This is the only study Aquamin offers on bone health. If you can send me the names of the companies from which you are able to purchase stronium where you are, I will look at their quality control standards and let you know which I would feel comfortable trusting. By staggering your intake, you allow both supplements to be absorbed properly and effectively. Glucocorticoid-induced osteoporosis.Clin Exp Rheumatol. K. Niu, R. Ahola, H. Guo et al., Effect of office-based brief high-impact exercise on bone mineral density in healthy premenopausal women: the Sendai Bone Health Concept Study, Journal of Bone and Mineral Metabolism, vol. It seems that the many benefits of lactoferrin are well known, but its effect on bone building are not so well documented. Strontium ranelate (PROTELOS), a new chemical entity containing stable strontium (Sr), was tested for its capacity to influence bone quality and quantity. Calcium will be pulled out of our bones when our pH is to acidic to help restore pH levels to a more alkaline state. A couple of months ago I saw new research suggesting that some people (a VERY few of us, obviously including the woman who wrote me) may be able to get by with less K2 these are persons with some rare SNPs that result in their keeping K2 around longer than the vast majority of us. None because of adverse effects on bone. Hi Anne, what you are doing sounds great. Is there a toxic level for K2 (MK7)? In the research, approximately 50% of the increase seen in BMD over 3 years of treatment with strontium was due to strontiums larger size, AND 50% of the increase seen in BMD was accurate. This dose will help protect and maintain the long-term health of your bones. Wnt signaling: Wnt signaling is involved in osteoblast production & activity; strontium triggers Wnt signaling. I have been breaking out in several small red itchy bumps all over my body and my skin feels chapped, including my eye lids. Just go very slowly and see what happens. Sorry, do not mean to hammer on you with questions. So, they were looking at short term (in comparison to the rest of a postmenopausal womans life span) outcomes. I typically give my 75lb boxer a can of sardines once a week and I give it to him all at once. Try this and your taste buds as well as your digestive tract and bones will be delighted with you. In research studies, hair loss has never been reported as a side effect of natural strontium salts (such as the strontium citrate in Strontium Boost). To learn about the most strontium-rich foods, check out our Strontium Food Sources page. I try to get around 400 mcg/day of MK-7 from supplements plus my diet. It is pretty value sufficient for me. Items left from my list of meds: Super Ubiquinol CoQ10 from LEF, Zinc 22 mgm, Chromium 50 mcg, daily and copper 2mg twice a week; manganese is picked up from CA/Mg supplement. Any suggestions on when to take? Thanks. Heres a recent paper on this: Pharm Res. I have osteoporosis and I really want to take 2 strontium before bed yet I need to function the next day. Strontium has nearly twice the atomic weight of calcium. You might consider taking a strontium citrate supplement providing approximately 680 milligrams of elemental strontiumthis is what Strontium Boost delivers, and there are other strontium citrate supplements available that also provide this dosage. Thanks Lara. Yes, my inflammation is under control. Im now not certain where youre getting your information, but great I hope this helps to ease your mind and answer your question, Mallika! It would be nice to just swallow one pill that would help bones and all else! And this applies to ANYTHING you see on the web. GENTLE + EASY TO DIGEST: Natures Nectar's Bone Builder is made with essential vitamins and minerals that are easy-to-digest and gentle on the body, even when taken on an empty stomach. Another issue to consider is that the strontium ranelate drug, Protelos, contains Aspartame an ingredient which is known for causing reactions on its own. I just noticed the warning on the label . I have to wait 4 hours after meal to take stontium (right) so I have to stay up late or end up getting up in the middle of the night to take strontium. If strontium promoted hair loss, dont you think it would have been noted in the last 100 years in the many thousands of subjects taking strontium in numerous clinical trials? I also take 4 capsules of the Algaecal Plus daily(lunch/dinner). DRESS syndrome is often severe and can result in death if not diagnosed early for which reason, youre urged to see your doctor immediately if you develop a rash after taking strontium ranelate. Strontium ranelate: dose-dependent effects in established 2001 Apr;28(4):446-53. Association between DHEAS and bone loss in postmenopausal women: a 15-year longitudinal population-based study. 2X better mineralization of Osteoblasts than CaCO3 and Ca Citrate Secondly, take your strontium at a different time of day from when you are consuming calcium. Thank you! I need more than this because I need more vitamin D3, so I take at least 240 mcg of MK-7 daily. Are you aware of the research on glutathione (given via nebulizer) for COPD it is VERY helpful! I do this by taking Triple Power, which in addition to EPA/DHA, also contains two very powerful but safe anti-inflammatory agents: curcumin and astaxanthin. Factors that raise a womans GAIL score are starting menstruation early (so more exposure to estrogens), age at first live birth (pregnancy and nursing lowers estrogen exposure for at least a year, longer if nursing), number of breast biopsies (checking b/c of indications of breast cancer), a history of atypical hyperplasia (abnormal excessive replication of breast tissue cells), and a history of lobular carcinoma in situ (breast cancer). I read in the discussion that a GFR of 50 or less would indicate that I should not take Strontium. Granted it refers to individuals with preexisting conditions, but still. I was taking Fasomac for three years with the doctors advice. I couldnt know for sure if this is the correct molar mass, because there is nowhere for an extra divalent ion (i.e. Now I am barely osteopenic and expect my next DXA will show I am fully in the healthy normal range. Shaine, Hi Shaine, I stopped taking for a few days& the diarrhea stopped. Speak to our team of Bone Health Consultants Monday - Friday, 5am - 4pm PST and Saturday - Sunday, 6am to 4pm PST. An individual on the osteoporosis Inspire site wrote about elevated blood serum levels due to her consumption of the supplement strontium. Sorry, I should have explained that venous thrombosis is medical-speak for a blood clot (thrombus) that forms within a vein. Here are links to this research (I see only one of the papers I cited is now provided as a link in the post on AlgaeCal.com. If you have chronic kidney disease, you should not risk taking strontium. Here s a link to Dr. Grouts website: http://www.arizonaadvancedmedicine.com Calcium and strontium compete for absorption, and calcium always wins, so you will not get benefit from the strontium if taken with calcium. Classic symptoms include widespread rash, fever, and involvement of one or more internal organs. I am not being paid to respond to questions here on this blog. Hi Tyler, Thats what I recommend for you. If so, have you had your blood levels of 25(OH)D checked? Therapeutically, radioactive strontium is used to treat metastatic cancer but can damage bone marrow and act as a potential carcinogen itself at high doses. Over-expression of the ERBB2 gene (also referred to as amplification), occurs in approximately 15-30% of breast cancers and has been shown to play a role in the development and progression of certain types (the ER+ or HER2/Neu+) breast cancers. Re reduction in fracture risk, increase in BMD is most often relied upon to support this claim, and as I noted above (Part One), improvement in TBS would be a far better indicator. Bovine lactoferrin improves bone mass and microstructure in ovariectomized rats via OPG/RANKL/RANK pathway. These studies aimed to evaluate using X-ray microanalysis, X-ray diffraction and computerized quantitative contact microradiography: (1) the relative calcium and Sr bone content, (2) the distribution of Sr in compact and cancellous bone, (3) the dose dependence of the deposition of Sr in bone, (4) the interactions between Sr and mineral at the crystal level (in monkeys), (5) the influence of Sr on the mean degree of mineralization of bone tissue and on the distribution of the degree of mineralization of bone tissue, and (6) the bone clearance of Sr over short periods of time (6 and 10 weeks) after cessation of SR administration (monkeys treated for 13 and 52 weeks, respectively). 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